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色素沉着部位主要在表皮层以及真皮层。真皮层的代谢非常缓慢，长达十年以上，大家可以看一下自己小时候手上，胳膊上留下的伤疤是不是到现在都没好，那就是因为真皮层受损了。
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皮秒激光的效果是比较好，它不会对皮肤造成很大的伤害，并且比较方便，病程比较短，不会耽误患者太长的时间，治疗之后不会留有疤痕。在治疗之后患者一定要注意皮肤的护理，避免在阳光中曝晒，这样阳光中的紫外线会对皮肤造成伤害，使治疗的效果降低。可以用防晒的用具，比如遮阳伞或者防晒霜。在日常生活中可以多吃富含维生素的食物，比如维生素c或者维生素e，多吃些新鲜的蔬菜和水果。平常要多走走路，多晒太阳，促进体内钙的合成和营养的吸收，养成良好的生活习惯，早睡早起，不要熬夜。
上上周跟一个朋友见面，我俩年龄差不多，都奔四了。刚坐下她就跟我抱怨脸上长了很多斑。其实我也是，虽然不是一眼能看到，但是自己照镜子时确实无法忽视。而且还是长在脸颊苹果肌的位置。前两年我的脸上几乎没有斑点，但是从去年开始这些不速之客开始冒出来，一个是光老化，年轻时候不懂防晒种下的因；另一个就是年龄的关系，皮肤的老化。所以说，年纪大了很多问题开始出现，真的是不服不行。
不仅仅是皮秒，多数色斑在打完激光后都会反黑，这是正常现象。除非是用皮秒做全面部清扫，否则几乎没法避免。出现了之后也不用担心，都会慢慢消退的。当然，黄褐斑因为情况比较复杂，到底是反黑还是病情加重，需要医生面诊。
接着，医生又仔细观察她的面部，还发现其他两种斑点——眼睛下方的褐青色痣，鼻翼鼻梁处小雀斑。现在，她完全顾不上如何缩小毛孔这种问题了，只想尽快去掉这些斑点。（@婷婷：没想到自己脸上的斑种类如此丰富……嗯……心情复杂）
皮秒激光是一种去除色素沉着的激光，使用特殊的波长直接作用于皮肤皮下细胞，使细胞破碎达到治疗的目的。 该种波长照射在皮肤表面后局部皮肤会出现红斑、丘疹、灼热、瘙痒等，严重者会出现破溃、糜烂，个别患者容易引发刺激性黄褐斑，主要是激光对皮肤表皮刺激后形成的，如果想要改善症状，建议可以选择在激光照射后在局部涂抹重组人表皮生长因子凝胶，或者选择使用冰镇矿泉水冷敷，可以有效的降低副作用发生的概率。 如果已经出现破溃、糜烂现象，需要选择使用生理盐水湿敷，可以使症状得到缓解。
我也就这个问题咨询过浙江皮肤病防治研究所的专家，他告诉我，没有哪种单一的、对皮肤安全无害的化学物质/动植物提取物可以实现彻底祛斑（重金属，激素可以祛斑，但是不用我说，大家都应该知道这些东西对皮肤的危害有多大），所以市面上绝大部分声称可以祛斑的产品要么是吹的要么是添加了重金属/激素，大家不要浪费钱了！